Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemETemocaprilhydrochloride(Standard)Cat.No.:HY-B0384RCASNo.:110221-44-8分子式:C??H??ClN?O?S?分子量:513.07作用靶點(diǎn):Angiotensin-convertingEnzyme(ACE)作用通路:MetabolicEnzyme/Protease儲(chǔ)存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性Temocapril(hydrochloride)(Standard)是Temocapril(hydrochloride)的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。Temocaprilhydrochloride是一種具有口服活性的血管緊張素轉(zhuǎn)化酶(ACE)抑制劑。Temocaprilhydrochloride可以用于高血壓、充血性心力衰竭、急性心肌梗死、胰島素抵抗和腎臟疾病的研究[1][2]。IC50&TargetACE[1]REFERENCESFukamiT,etal.Invitroevaluationofinhibitoryeffectsofantidiabeticandantihyperlipidemicdrugsonhumancarboxylesteraseactivities.DrugMetabDispos.2010Dec;38(12):2173-8.KawasakiH,etal.Angiotensininhibitsneurotransmissionofcalcitoningene-relatedpeptide-containingvasodilatornervesinmesentericarteryofspontaneouslyhypertensiverats.JPharmacolExpTher.1998Feb;284(2):508-15.YuanZ,etal.Temocapriltreatmentamelioratesautoimmunemyocarditisassociatedwithenhancedcardiomyocytethioredoxinexpression.CardiovascRes.2002Aug1;55(2):320-8.OhnishiK,etal.Angiotensin-convertingenzymeinhibitordoesnotsuppressrenalangiotensinIIlevelsinangiotensinI-infusedrats.JPharmacolSci.2013;122(2):103-8.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:0