1、ICS 13. 100C 70DB12天 津 市 地 方 標(biāo) 準(zhǔn)DB12/T 8812019化學(xué)毒物職業(yè)病危害風(fēng)險評價技術(shù)指南Technical guidelines of risk assessment for chemical toxicant occupational hazard2019-05-01 實施2019-03-25 2019-05-01 實施天津市市場監(jiān)督管理委員會DB12/T 8812019DB12/T 8812019 附錄M（資料性附錄）常見確認人類化學(xué)致癌物的吸入單位風(fēng)險表M.1常見化學(xué)致癌物的吸入單位風(fēng)險化學(xué)致癌物化學(xué)文摘號（CAS No.）導(dǎo)致腫瘤的種類吸入單位風(fēng)險

2、（虻/靛）苯71-43-2白血病2. 2 X10 7. 8X10-6 a氯乙烯75-01-4肝血管肉瘤4.4 X10-6聯(lián)苯胺92-87-5膀胱癌6. 7 X10-2六價銘化合物18540-29-9肺癌1. 2X10-21,3-T 二烯106-99-0白血病3X10-5雙氯甲醍542-88-1肺癌6. 2X10-2碑及其無機化合物7440-38-2肺癌4. 3X10-3鍛及其化合物7440-41-7肺癌2.4X10-3鎘及其化合物7440-43-9肺、氣管、支氣管腫瘤1. 8X10-3環(huán)氧乙烷75-21-8淋巴癌、（女性）乳腺癌3X10-3三氯乙烯79-01-6腎細胞癌、非霍奇金淋巴瘤和肝腫瘤

3、4. 1X10*a苯的致癌風(fēng)險計算可按吸入單位風(fēng)險區(qū)間計算超額風(fēng)險區(qū)間或按吸入單位風(fēng)險上限估計超額風(fēng)險的上限。附錄N（資料性附錄）化學(xué)致癌物超額風(fēng)險的計算示例N. 1苯職業(yè)暴露導(dǎo)致白血病的超額風(fēng)險計算示例1假設(shè)某企業(yè)苯職業(yè)暴露工人作業(yè)方式以巡檢為主，苯職業(yè)暴露地點不固定，檢測得到該崗位作業(yè)工 人接觸苯的8小時時間加權(quán)平均濃度為l.Omg/mL 一年按52周，每周工作4天，假設(shè)作業(yè)工人在該崗位 工作25年，按公式（8）計算終身平均調(diào)整濃度，按公式（9）計算超額風(fēng)險。air-adj= 1.0 x8x(4x52)x25613200-air-adj= 1.0 x8x(4x52)x25613200-=0

4、.068 mg/m3Risktumor =（2.2xW6 7.8xlOxlO3 x 0.068= 1.5 xW4 5.3xW4該崗位作業(yè)工人苯致癌超額風(fēng)險超過致癌可接受風(fēng)險水平1. 0X104oN. 2苯職業(yè)暴露導(dǎo)致白血病的超額風(fēng)險計算示例2假設(shè)某企業(yè)苯職業(yè)暴露工人的苯職業(yè)暴露作業(yè)地點相對固定、暴露時機相對集中，檢測得到該作業(yè) 環(huán)境下，苯短時間接觸濃度為3. 0 mg/m作業(yè)工人每周工作4天，每天暴露于該作業(yè)環(huán)境2小時，假設(shè) 作業(yè)工人在該崗位工作25年，一年按52周，按公式（8）計算終身平均調(diào)整濃度，按公式（9）計算超額 風(fēng)險。air-adj=3.Ox2x(4x52)x25613200-air

5、-adj=3.Ox2x(4x52)x25613200-=0.051 mg/m3=（2.2xl0-67.8xl06）xltf x0.051=l.lxl04 4.0 xW4該崗位作業(yè)工人苯致癌超額風(fēng)險超過致癌可接受風(fēng)險水平1. 0X104o參考文獻Ministry of Manpower Occupational Safety and Health Division. A Semi-Quantitative Method to Assess Occupational Exposure to Harmful ChemicalsZ, 2005ELSEVIER. Knovel Sampler-Calcu

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