Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemERanolazinedihydrochloride(Standard)Cat.No.:HY-17401RCASNo.:95635-56-6分?式:C??H??Cl?N?O?分?量:500.46作?靶點:CalciumChannel;SodiumChannel;Autophagy作?通路:MembraneTransporter/IonChannel;NeuronalSignaling;Autophagy儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Ranolazine(dihydrochloride)(Standard)Ranolazine(dihydrochloride)的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。Ranolazinedihydrochloride(CVT303dihydrochloride)?種抗?絞痛和抗缺?劑，可通過抑制內(nèi)向鈉電流的后期作?(對INa和IKr的IC50值分別為6IC50&TargetIC50:6μM(INa),12μM(IKr)[1]REFERENCES[1].KeatingGM.Ranolazine:AReviewofItsUseasAdd-OnTherapyinPatientswithChronicStableAnginaPectoris.Drugs.2013Jan;73(1):55-73.[2].WangWQ,RobertsonC,DhallaAK,BelardinelliL.Antitorsadogeniceffectsof({+/-})-N-(2,6-dimethyl-phenyl)-(4[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazine(ranolazine)inanesthetizedrabbits.JPharmacolExpTher.2008Jun;325(3):875-81.doi:10.1124/jpet.108.137729.Epub2008Mar5.[3].ZacharowskiK,BlackburnB,ThiemermannC.Ranolazine,apartialfattyacidoxidationinhibitor,reducesmyocardialinfarctsizeandcardiactroponinTreleaseintherat.EurJPharmacol.2001Apr20;418(1-2):105-10.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:02