Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEOtenaproxesul(Standard)Cat.No.:HY-15028RCASNo.:1226895-20-0分?式:C??H??NO?S分?量:365.45作?靶點(diǎn):COX;Apoptosis作?通路:Immunology/Inflammation;Apoptosis儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性O(shè)tenaproxesul(Standard)Otenaproxesul的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。Otenaproxesul(ATB-346)具有?服活性的、?甾體抗炎藥(NSAID)，可抑制環(huán)氧合酶-1和2(COX-1，2)。Otenaproxesul具有抗炎?物活性，可?于緩解疼痛的研究。REFERENCES[1].JohnLWallace,etal.Markedlyreducedtoxicityofahydrogensulphide-releasingderivativeofnaproxen(ATB-346).BrJPharmacol.2010Mar;159(6):1236-46.[2].PaolaDeCicco,etal.ATB-346,anovelhydrogensulfide-releasinganti-inflammatorydrug,inducesapoptosisofhumanmelanomacellsandinhibitsmelanomadevelopmentinvivo.PharmacolRes.2016Dec;114:67-73.[3].BrunoSchneiderHerrera,etal.TheH2S-releasingnaproxenderivative,ATB-346,inhibitsalveolarbonelossandinflammationinratswithligature-inducedperiodontitis.MedGasRes.2015Feb27;5:4.[4].panelEduardoEkundi-Valentim,etal.P4AntiinflammatoryandantinociceptiveeffectsofATB-346,agastricsparinghydrogensulfide-releasingnaproxen,inratswithcarrageenan-inducedkneejointsynovitis.NitricOxide.Volume27,Supplement2,15September2012,PageS13.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax: