Chromeleon6.8JimSchiblerFraserMcLeodWhat’sNewinChromeleon6.8Fullcontrolofevenmoreinstruments(nowtotalingover260!)Unique,innovativecontrolfeaturesfornewUltiMate3000systemsDual-ComponenteluentgenerationforICS-2000ICsystemsEnhancedTrending,Suitability,3DAmperometry,andmoreFullControlofEvenMoreInstrumentsUltiMate3000SeriesHPLCSystemsPolymerLabsELS2100EvaporativeLight-ScatteringDetectorShimadzu2010GasChromatographShimadzuM10AandM20PhotodiodeArrayDetectorsPerkin-Elmer200SeriesHPLCSystemsGilson331/332PumpsAgilent7683GCAutosamplertogetherwith5890GCFluke189MultimeterChromeleoncontrolsover260instrumentsfrommorethan25manufacturersFeaturesforUltiMate3000SystemsSmartStartupSmartShutdownSystemQualificationPredictivePerformanceWizardforOn-LineSPESystemDiagnosticsTroubleshootingGuidesSharedDevicesUnique,innovativecontrolfeaturesUltiMate3000:SmartStartupSavestime,preventserrorsAutomatessystemequilibrationprocessNoneedtowatchandwait–batchstartswhensystemisreadySimplewizardguidessetupofequilibrationconditionsforeachsystemmoduleMultiplesetsofstartupconditionscanbesavedandre-usedUltiMate3000:SmartShutdownSavestime,preventserrorsAutomatessystemshutdownprocessChoosefullshutdownorlow-flowstandbyShutdown/standbyprogramautomaticallyappendedtobatchUltiMate3000:SystemQualificationAllUltiMatemodulesfullysupportedbyChromeleon’sAutoQ?AutomatedQualificationSuiteAdministratorcanrestrictuseofmoduleswithexpiredqualification=>helpslabsstayGLP-compliantQualificationintervalscanbeeasilydefinedvianewslidergaugetoolsincontrolpanelsQualificationdatastoredinfirmware =>alwaysstaywiththemodules,easilyandreliablyretrievedUltiMate3000:PredictivePerformanceEach

module

hascountersinfirmwarethatcontinuouslytrackusageofwearpartsWarningandexpirationlimitscanbesetforeachcounterusingnewslidergaugecontrolsReadyCheckassessescurrentwearstatus,warnsifanylimitshavebeenexceededEasiermaintenancescheduling,lessunexpecteddowntimeUltiMate3000:WizardforOn-LineSPESamplepreparationmadeeasierBackflushanalytesfromextractorSeparateanalytes,loadnextsampleSimplifiessetupofcomplexsolid-phaseextractionproceduresTakesadvantageofdual-pumpcapabilitiesofUltiMate3000ExtractorColumnSeparatorColumnExpandedEluentOptionsforICS-2000CO3/HCO3

eluents,reagent-free!LiOH,NaOHalsosupportedSupportedbyallnewICS-2000sRetrofitavailableforpriorICS-2000sInChromeleon6.8,6.7SP3,6.6SP6CarbonateeluentgenerationnowavailableinanintegratedRFICsystemOther6.8EnhancementsTrending:controlchartingwithdifferentlimitsfordifferentanalytesSuitability:signal-to-noise,drift,roundingcontrol,aggregatereports3DAmperometry:I-tplots(analogoustospectra)forpeaks,timesSystemStatusreport:singlefilecapturingalldetailsofstationstateVirtualColumn:newmodelingforAS11-HC,AS16,AS20,CS-17TrendingEnhancementsAnalyte-specificlimitsforcontrolchartingHyperlinkingbetweenquery-generatedtrendpointsandtheirsourcechromatogramsEnhancedsupportforquality-controlapplicationsSystemSuitability:Signal/NoiseRatioSignal/noiseratioisacommonlyrequiredsystemsuitabilitytestCalculationstraditionallyhavehadtobedonemanuallyChromeleon6.8makesautomatedsignal/noisecalculationeasy!Availableforsuitability,reporttables,peaklabels,trending...SystemSuitability:Range(Drift)TestsFacilitatetestingforlong-termvariationApplicabletoanyChromeleonvariablebackgroundsignal,pressure,retentiontime...Average,Range,RelativeRangeoptionsSystemSuitability:RoundingControlRoundingoptionsgivebettercontrolofPass/FailconditionsSystemSuitability:AggregateTablesNewtabletypeprovidesindividualresultsandoverallresultsforaggregatetests(testsperformedacrossmultiplesamples)Clear,transparentdocumentationofcomplexsuitabilitytests3-DAmperometryEnhancementsKeyimprovementstoexpanduseofthisinnovativedetectiontechniqueI-tplotoverlays(likespectra)selectedpointsonapeakselectedtimesinchromatogramdifferentsamplesFastrenderingoflarge3-DfieldsSystemStatusReportEasilygeneratedande-mailed“snapshot”file–simplifiestechnicalsupportVirtualColumnSeparationSimulatorNowsupportinggradientAS11-HC,AS16,CS17andisocraticCS17SeparatorsModeledbyVirtualColumnColumn

Eluent

Modes

KeyapplicationsAS20 Hydroxide I TraceperchlorateusingsuppressedconductivitydetectionAS19 Hydroxide I G Inorganicanionsandoxyhalides;tracebromateAS18 Hydroxide I G CommoninorganicanionsAS17 Hydroxide G FastgradientRFICanalysisofcommoninorganicanionsAS16 Hydroxide I G

Polarizableanions,polyvalentanionsAS15 Hydroxide I G InorganicanionsandsmallorganicacidsinhighpuritywaterAS14A Carbonate I FastanalysisofcommoninorganicanionsAS14 Carbonate I CommoninorganicanionsAS12A Carbonate I Inorganicanions,oxyhalides,trace-levelanionsAS11-HC Hydroxide I G OrganicacidsandinorganicanionsinuncharacterizedsamplesAS11 Hydroxide G Organicacidsandinorganicanionsinwell-characterizedsamplesAS10 Hydroxide I InorganicanionsandorganicacidsinhighnitratesamplesAS9-HC Carbonate I InorganicanionsandoxyhalidesAS4A-SC Carbonate I FastanalysisofcommoninorganicanionsCS17 MSA I G Hydrophobicandpolyvalentamines,biogenicamines,diaminesCS16 MSA I G Highratiosofsodiumandammonium;alkylaminesandalkanolaminesCS12A MSA I Inorganiccations;morpholine;alkyl,aromatic,andquaternaryaminesPA-20 Hydroxide I MonosaccharidesI=Isocratic,G=GradientListiscurrentasofChromeleon6.8;itemsinyellowwereaddedsincereleaseof6.7What’sNewinChromeleon6.8Fullcontrolofevenmoreinstruments(nowtotalingover260!)Unique,innovativecontrolfeaturesfornewUltiMate3000systemsDual-ComponenteluentgenerationforICS-2000ICsystemsEnhancedTrending,Suitability,3DAmperometry,andmoreChromeleon6.8JimSchiblerFraserMcLeodQuizonChromeleon6.8Forwhichinstrumentsissupportbeingaddedby6.8?UltiMate3000Capillary/NanoLCSystemsShimadzu2010HPLCICS-3000DualEluentGeneratorAgilent7673GCAutosamplerPolymerLabsEvaporativeLight-ScatteringDetectorQuizonChromeleon6.8Whichfitthemeaningof“PredictivePerformance”?EarlymaintenancefeedbackTestsperformedbeforeanalysestoensuresystemsuitabilityOptimizedseparationsdevelopedusingVirtualColumnContinuousstatusmonitoringofwearpartsProjectedcolumnlifetimesusingTrendcontrolchartsAutomatedqualification+qual