1、腦梗死后失眠論文：腦梗死后失眠益腎活血法療效和安全性觀察【中文摘要】觀察以益腎活血法立方的中藥煎劑治療腎陰虛兼血瘀型缺血性腦卒中后失眠的療效和安全性，評價益腎活血法在缺血性腦卒中后失眠治療中的作用。方法：將60例腎陰虛兼血瘀型缺血性腦卒中后失眠的患者隨機(jī)分為治療組和對照組各30例。2組基礎(chǔ)治療用藥相同，治療組采用中醫(yī)藥益腎活血法治療，對照組采用西藥艾司唑侖治療。觀察治療前后患者臨床療效、PSQI積分及TESS評分的變化。療程為4周。結(jié)果：1.臨床療效：治療組與對照組均能顯著改善失眠臨床癥狀，但比較后差異無統(tǒng)計學(xué)意義。2.應(yīng)用PSQI進(jìn)行睡眠質(zhì)量評價：治療組的臨床總有效率高于對照組，但經(jīng)檢驗后差

2、異無統(tǒng)計學(xué)意義；以PSQK7分為癥狀完全緩解率比較，治療組高于對照組，經(jīng)檢驗差異有顯著性。3.各時段PSQI評分比較：治療組與對照組較治療前均有不同程度的下降。治療組1周后療效不如西藥鎮(zhèn)靜安眠藥兩組比較P0.05,無統(tǒng)計學(xué)意義，但臨床痊愈率不如西藥鎮(zhèn)靜安眠藥；服用4周后療效與西藥鎮(zhèn)靜安眠藥比較P>0.05,無顯著性差異。4.療程結(jié)束時,進(jìn)行副反應(yīng)量表（TESS）評分：治療組平均積分明顯低于對照組。兩組比較P<0.05,差異有統(tǒng)計學(xué)意義。5.中醫(yī)證候療效：治療組有效率高于對照組，經(jīng)檢驗差異達(dá)顯著水平。結(jié)論：1.益腎活血法可以改善缺血性腦卒中后失眠（腎陰虛兼血瘀型）患者的睡眠質(zhì)量，有較

3、好的臨床療效，可達(dá)到與西藥艾司唑侖相似的臨床效果。2.應(yīng)用中藥治療長期療效穩(wěn)定，副反應(yīng)少，但起效不如西藥艾司唑侖迅速。3.益腎活血法能改善缺血性腦卒中后失眠患者的癥狀、體征和中醫(yī)證候積分。【英文摘要】：Toobservetheefficacyandsafetyofthisdecoctionestablishedbytheprincipleofnutritioningkidneyyinandactivatingbloodwhichusedinthetreatmentoftheaypniaafterischemicstroke,evaluationingtheroleofTCMmethodsint

4、hetreatmentoftheaypniaafterischemicstrokeMethod:60patientsofaypniaafterischemicstroke(combinationofbloodstasisandkidney-yindeficiency)wererandomlydividedintotreatmentgroup(n二30)andcontrolgroup(n二30).Twogroupsarebothacceptedconventionaltreatment.Thetreatmentgroupaddedthedecoctionestablishedbytheprinc

5、ipleofnutritioningkidneyyinandactivatingblood.Thecontrolgroupaddedestazolam.ObservetheclinicalefficacyandthechangementofintegralsofPSQIandTESSbeforeandaftertreatment.Bothtrialscontinuedfor4weeks.Result:1.Aypniaclinicalefficacy:thediffereneebetweentreatmentgroupandtreatmentgroupwerenotsignificantly(P

6、>0.05).2.ToevaluatesleepqualitybymeansofPSQI,clinicaltotaleffectiverateintreatmentgroupwashigherthanthatincontrolgroup,butthediffereneewasnotsignificant(P>0.05).PSQI0.05,butclinicalcurerateofthecontrolgroupwaslower;Take4weeksaftercurativeeffectofthemwasnotsignificantdifferencesP>0.05.4.Atth

7、eendofthecourse,comparedwithTESSscore,thetreatmentgroupfor(4.28士0.54)pointswaslowerthanthecontrolgroupfor(13.15士2.73)points.Thediffereneewasstatisticalsignificanee(P<0.05).5.TCMsymptomaticcurativeeffect:effectiverateinthetreatmentgroupwassignificantlyhigherthanthatincontrolgroup,therewassignifica

8、ntdiffereneeP<0.05.Conclusion:1.NutritioningkidneyYinandpromotingbloodcirculationtotreattheaypniaafterischemicstrokehadgoodtherapeuticeffectwhichwassimilartousingestazolam2.Tocomparedwithwesternmedicineestazolam,herbaldecotionhaseffectmoreslowly,butIong-termstability,lesssideeffects.3.Thedecotioncanimproveaypniaafterischemicstrokensymptomsandsigns,andTCMsymptomaticscores.【關(guān)鍵詞】腦梗死后失眠益腎活血法療效和安全性觀察【采買全文止】139938.848138413.721同時提供論文寫作一對一輔導(dǎo)和論文發(fā)表服務(wù).保過包發(fā).【說明】本文僅為中國學(xué)術(shù)文獻(xiàn)總庫